Located in the heart of Boston’s prestigious Longwood Medical Area, the laboratories comprise 13 floors above-grade and seven floors below-grade for parking and mechanical space. Two bridges connect the facility to adjacent Dana-Farber buildings at intermediate levels. The facility houses laboratories and support space to advance Dana-Farber Cancer Institute’s world renowned research to identify the causes and cures of cancer. The first floor of the building houses a large lobby, loading areas and building support space. Dry lab space for epidemiology is located on the second floor. The upper floors house private laboratory spaces and a biosafety level three (BL3) animal facility with air locks and a high level of biochemical security. The biomedical research laboratories located on these floors include a support core at the center that houses glass wash, equipment, environmental and isotope rooms. The laboratories were designed to facilitate the reconfiguration of space to accommodate evolving research technologies and uses. Offices are located at the corners of the building, and glass curtain walls covering those areas offer a view of the city.